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The Grand Finale of Dutch 4TU. Impact Challenge

The teams for the 4TU Impact Challenge are selected through preliminary rounds held at each of the four leading Dutch technical universities: TU Delft, TU Eindhoven, University of Twente, and Wageningen University & Research. Ambitious student teams pitch their ideas and innovations to a panel of expert judges. Selection is based on key criteria such as originality, technical feasibility, market potential and societal impact. Only the most promising and visionary concepts move on to the national final.

The final takes place at Fuse Enschede, the leading Dutch startup event in the Netherlands (Thursday, August 27th at the U Parkhotel).  There are two awards to win at the 2026 4TU Impact Challenge: the Startup Award and the Spin-off Award. Both winning teams will earn a place on one of the 4TU Federation’s international startup missions, such as a high-profile conference or trade mission. This opportunity not only offers global exposure, but also connects winners with investors, partners, and valuable networks. Additionally, they’ll earn the title of ‘Best Startup/Spin-off Team of the 4TU.’ for the year - celebrating their innovation and social impact. Together, these rewards provide both recognition and a springboard to accelerate their positive change.

CHECK THE AFTERMOVIE
Finalists
SimplyPill
SimplyPill is the first medication use ecosystem that combines an intelligent pill dispenser, connected app, and real-world adherence data to transform how patients, providers, and pharmaceutical partners manage medication routines.
University of Twente
Bloombouy
Bloombouy is an aesthetic eco-adaptation that enhances biodiversity at every level within degrading waterways: pollinators in the air, floating insects on the surface, and aquatic life below.
Wageningen University & Research
Heatlift Dynamics
HeatLift Dynamics enables the business case for industrial heat pumps by improving heat pump efficiency by up to 30% through their novel Multiphase Pressure Exchanger (MPE)
Delft University of Technology
MOTEX
MOTEX develops a predictive safety system for motorcyclists that anticipates traffic risks and alerts riders in real time to help prevent accidents.
Eindhoven University of Technology
TutorMe
TutorMe is a Peer-to-Peer student tutoring platform which is becoming a one stop shop for all students academic needs.
University of Twente
Sea to Skin (S2S)
Sea to Skin (S2S) is an innovative biorefinery that transforms brown seaweed into fucoxanthin and alginate, offering a sustainable, reef-safe alternative for skin care and cosmetics while addressing waste in conventional seaweed processing.
Wageningen University & Research
Vindi Biosystems
Transforming healthcare from reactive to proactive with Vindi Biosystems
Delft University of Technology
FABBS
FABBS takes batteries to the next level with intelligent energy management for optimal performance from every cell.
Eindhoven University of Technology
PREPARING FOR THE FINAL..
BOOTCAMP (27TH OF AUGUST)

During the 4TU. Bootcamp which will be held on the 26th, the teams will follow two workshops to prepare them and make the most out of their FUSE experience! After this, the student startups will meet the jury during the Dragon’s Den followed by a networking BBQ and drinks with the teams, fellow jury members, investors and speakers that will attend FUSE Enschede.

JURY MEMBERS
Anja Sinke
Jury Chair | Member of the Supervisory Board | SER-Topvrouwen.nl | Startup Mentor
Rutger de Graaf
Team Lead Startup & Scale-up Policy at the Dutch Ministry of Economic Affairs and Climate Policy
Femke Markus
Investor, Chairman of the Board, Strategy Expert, Delft Female Impact Fund
Mason Sinclair
Deep Tech Investor, Principal at IQ Capital, University of Cambridge
Qurein Biewenga
Fund Manager PhotonDelta | Co-Founder at Lightyear | Startup Advisor

RECAP: Vindi Biosystems and SimplyPill won the 7th edition of the 4TU Impact Challenge.

The seventh edition of the 4TU Impact Challenge took place in August 2025 at University of Twente, where start-ups from the four technical universities competed for the Jury and Audience Awards. Vindi Biosystems from Delft won the Jury Award with their wearable device for real-time monitoring of up to 24 biomarkers, enabling early detection and continuous insight into diseases such as heart failure. The Audience Award went to SimplyPill from Twente, an innovative smart pill dispenser connected to an app that improves medication adherence and provides real-time insight into medication use for patients and healthcare providers.